Program
Program at aProgram
| Thursday, 16 May, 2019 | ||
| 19:15~ | Presidential Reception at Toba Aquarium *The aquarium will be reserved from 18:45 for our reception. *All participants of the symposium will be welcomed regardless whether or not you are a chair or a speaker. |
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| Friday, 17 May, 2019 | ||
| 8:30~8:35 | Opening Remarks | |
| 8:35~9:05 | Special Session 1 | |
| Chair | Kinuko Mitani (Dokkyo Medical University School of Medicine) | |
| Speaker | Hiroto Inaba (St. Jude Children’s Research Hospital, USA) Precision medicine in pediatric acute lymphoblastic leukemia: a strategy to cure all patients and decrease adverse effects |
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| 9:15~10:35 | Asia-Pacific Session 1 : Bone Marrow Failure | |
| Chairs | Shouichi Ohga (Kyushu University Graduate School of Medical Sciences) | |
| Yoshiyuki Takahashi (Nagoya University Graduate School of Medicine) | ||
| Speakers | Atsushi Narita (Nagoya University Graduate School of Medicine) Randomized trial of two dosages of rabbit antithymocyte globulin in patients with aplastic anemia |
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| Jing Chen (Shanghai Children’s Medical Center, Shanghai Jiao Tong University School of Medicine, China) Upfront alternate donor HSCT for patients with severe aplastic anemia: multi-center prospective clinical trial outcome |
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| Ken Ishiyama (Kanazawa University Hospital) Factors affecting response to eltrombopag in patients with refractory aplastic anemia |
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| Jong Wook Lee (Seoul St. Mary's Hospital, The Catholic University of Korea, Korea) Safety and efficacy of romiplostim in aplastic anemia refractory to immunosuppressive therapy |
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| 9:15~10:35 | Asia-Pacific Session 2 : Neoplastic Lymphoid Cells | |
| Chairs | Shigeru Chiba (Faculty of Medicine, University of Tsukuba) |
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| Motoko Yamaguchi (Mie University Graduate School of Medicine) | ||
| Speakers | Kotaro Arita (Toyama University Graduate School of Medicine and Pharmaceutical Sciences) Establishment of a mouse model of B-cell lymphoma using an in vitro retroviral transduction system |
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| Constantine S Tam (St. Vincent Hospital, Peter MacCallum Cancer Center and University of Melbourne, Australia) Exploiting weaknesses in the malignant lymphoid cell for targeted therapy |
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| Mamiko Sakata-Yanagimoto (Faculty of Medicine, University of Tsukuba) Genome-based medicine in peripheral T-cell lymphomas |
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| Yok-Lam Kwong (Queen Mary Hospital, China) Immune-Checkpoint Inhibition in T-cell and NK-cell Malignancies |
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| 10:35~10:45 | Break | |
| 10:45~12:25 | Plenary Session 1 : T Cells (Normal, Pathologic, and Modified) and Antigen-Presenting Cells | |
| Chairs | Norimitsu Kadowaki (Faculty of Medicine, Kagawa University) | |
| Itaru Matsumura (Kindai University Faculty of Medicine) | ||
| Speakers | Ken-ichi Matsuoka (Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences) In vivo modulation of regulatory and effector T cell homeostasis for maximization of GVL effect in allogeneic HSCT |
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| Zwi N. Berneman (Antwerp University Hospital and University of Antwerp, Belgium) Dendritic cell vaccination: correlation of clinical effects with T-cell response |
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| Naoki Hosen (Osaka University Graduate School of Medicine) The activated conformation of integrin β7 is a novel multiple myeloma–specific target for CAR T-cell therapy |
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| Madhav Dhodapkar (Emory University, USA) Targeting tissue residence and innate immunity towards protective immunity |
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| 12:25~12:35 | Break | |
| 12:35~13:20 | Luncheon Seminar 1 ( Co-Sponsored by Eisai Co., Ltd. ) | |
| Chair | Kinuko Mitani (Dokkyo Medical University School of Medicine) | |
| Speaker | Ulrich Jäger (Medical University of Vienna, Austria) Precision medicine of lymphoma based on genetics |
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| Luncheon Seminar 2 ( Co-Sponsored by Chugai Pharmaceutical Co., Ltd. ) | ||
| Chair | Norio Komatsu (Juntendo University School of Medicine) | |
| Speaker | Anthony G. Letai (Dana-Farber Cancer Institute, Harvard Medical School, USA) Future prospects for targeting apoptosis in hematopoietic malignancies |
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| 13:20~14:10 | Poster Viewing | |
| 14:10~15:50 | JSH/ASH Joint Session : Normal & Pathologic Hematopoietic Stem Cells | |
| Chairs | Yasushi Miyazaki (Atomic Bomb Disease Institute, Nagasaki University Graduate School of Biomedical Sciences) | |
| Kazuya Shimoda (Faculty of Medicine, University of Miyazaki) |
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| Speakers | Fumihiko Ishikawa (RIKEN Center for Integrative Medical Sciences) Developing therapeutic strategies for genetically-complex acute myeloid leukemia |
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| Ravi Majeti (Stanford University School of Medicine, USA) Stem cells in human AML |
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| Seishi Ogawa (Graduate School of Medicine, Kyoto University / Karolinska Institute, Sweden) Germline DDX41 mutations in the Japanese populations |
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| Anthony G. Letai (Dana-Farber Cancer Institute, Harvard Medical School, USA) Guiding blood cancer therapy with mitochondrial BH3 profiling |
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| 15:50~16:05 | Break | |
| 16:05~17:45 | Plenary Session 2 : Ex Vivo Generation of Blood Cells | |
| Chairs | Akifumi Takaori-Kondo (Graduate School of Medicine, Kyoto University) | |
| Kohshi Ohishi (Mie University Hospital) | ||
| Speakers | Shin-ichiro Fujii (RIKEN Center for Integrative Medical Sciences (IMS) / RIKEN Drug Discovery and Medical Technology Platforms (DMP)) Establishment of a new therapeutic cancer vaccine inducing multifunctional immunity, “artificial adjuvant vector cells (aAVC)” |
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| Jeffrey S. Miller (University of Minnesota, Masonic Cancer Center, USA) Novel ways to activate NK cells with specificity to treat cancer |
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| Koji Eto (CiRA, Kyoto University / Graduate School of Medicine, Chiba University) Turning stem cells into platelets for next generation transfusion |
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| Irwin D. Bernstein (Fred Hutchinson Cancer Research Center, University of Washington, USA) Notch signaling: enhancing the ex vivo generation of cells for therapeutic application |
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| 17:45~17:55 | Break | |
| 17:55~18:25 | Oral Session from Poster Presentation : Hematological Malignancies and Their Therapies, Clonal Hematopoiesis | |
| Chairs | Masahiro Hirayama (Mie University Graduate School of Medicine) | |
| Tetsuya Nosaka (Mie University Graduate School of Medicine) | ||
| Welcome Reception | ||
| Saturday, 18 May, 2019 | ||
| 8:00~8:45 | Morning Seminar 1 ( Co-Sponsored by Novartis Pharma K.K. ) | |
| Chair | Yuzuru Kanakura (Osaka University Graduate School of Medicine) | |
| Speaker | Itaru Matsumura (Kindai University Faculty of Medicine) Current Status and Future of CML Treatment |
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| Morning Seminar 2 ( Co-Sponsored by Pfizer Japan Inc. ) | ||
| Chair | Hitoshi Kiyoi (Nagoya University Graduate School of Medicine) | |
| Speaker | Takahiro Yamauchi (Faculty of Medical Sciences, University of Fukui) The Beginning of the New Era of R/R ALL treatment with BESPONSA (Inotuzumab ozogamicin) |
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| 8:45~8:55 | Break | |
| 8:55~9:25 | Special Session 2 | |
| Chair | Yuzuru Kanakura (Osaka University Graduate School of Medicine) | |
| Speaker | Makio Ogawa (Medical University of South Carolina, USA) My research career in the US medical system |
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| 9:25~9:40 | Break | |
| 9:40~11:20 | JSH/EHA Joint Session : Normal & Pathologic B Cells | |
| Chairs | Ulrich Jäger (Medical University of Vienna, Austria) | |
| Junji Suzumiya (Shimane University Hospital) | ||
| Speakers | Tomohiro Kurosaki (WPI Immunology Frontier Research Center, Osaka University / RIKEN Center for Integrative Medical Sciences (IMS)) Function of memory B cells and their generation mechanism |
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| Hermann Einsele (University Hospital Würzburg, Germany) T cell redirecting strategies in the treatment of B-cell and myeloid malignancies |
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| Koji Kato (Kyushu University Graduate School of Medical Sciences) A germinal center-associated microenvironmental signature predicts clinical outcome of diffuse large B-cell lymphoma |
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| Ulrich Jäger (Medical University of Vienna, Austria) Drug sensitivity testing for treatment-decisions in B-cell-lymphomas |
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| 11:20~11:30 | Break | |
| 11:30~12:15 | Luncheon Seminar 3 ( Co-Sponsored by Bristol-Myers Squibb K.K. ) | |
| Chair | Koichi Akashi (Kyushu University Graduate School of Medical Sciences) | |
| Speaker | Hermann Einsele (Universitiy of Würzburg, Germany) Immunotherapy for multiple myeloma targeting CD38, SLAMF7 and the future |
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| Luncheon Seminar 4 ( Co-Sponsored by NIPPON SHINYAKU CO., LTD. ) | ||
| Chair | Masahiro Kizaki (Saitama Medical Center, Saitama Medical University) | |
| Speaker | Ravi Majeti (Stanford University School of Medicine, USA) Clonal Evolution in Human AML |
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| 12:15~12:25 | Break | |
| 12:25~12:55 | Special Session 3 | |
| Chair | Koichi Akashi (Kyushu University Graduate School of Medical Sciences) | |
| Speaker | Hiroshi Shiku (Mie University Graduate School of Medicine) Adoptive cell therapy with TCR-Gene engineered T cells and beyond |
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| 12:55~13:00 | Closing Remarks | |
